How do Ashvattha’s Precision Nanomedicines Work? Precision Nanomedicine Targeting Activated Cells in Regions of Inflammation Precise Targeting to Activated Cells in Regions of Inflammation Eliminating Off Target Toxicity to Improve Patient Outcomes Characteristics of our Precision Nanomedicines Selective Uptake – only by activated inflammatory cells in diseased tissue Systemic Delivery – oral or injectable Crosses Tissue Barriers – blood/brain; blood/retinal Lack of Off-target Toxicity – safe at high doses Sustained Intracellular Effects – weeks to months, possibility for less frequent dosing Tunable for Each Indication and Target Low-cost Manufacture – and rapid discovery process Selective: Nanomedicine Uptake by Activated Inflammatory Cells in Regions of Disease