How do HDTs work?
Precision Nanomedicine Targeting Only Diseased Tissues
Precise Targeting to Diseased Tissues Eliminating Toxicity to Improve Patient Outcomes
HDs Have All the Characteristics of an Ideal Targeted Nanomedicine
- Selective Uptake – only by reactive inflammatory cells in diseased tissue (w/o ligand)
- Systemic Delivery – oral or injectable
- Crosses Tissue Barriers – blood/brain; blood/retinal
- Lack of Off-target Toxicity – safe at high doses
- Sustained Intracellular Effects – weeks to months
- Tunable for Each Indication and Target
- Low-cost Manufacture – and rapid discovery process
Selective: HDT Uptake in Reactive and Diseased Cells
